目的加强对重症急性胰腺炎(SAP)的认识,总结重症急性胰腺炎的治疗经验。方法回顾性分析2003年至2005年收治的33例重症急性胰腺炎病例的临床资料。其中男25例,女8例,年龄22~85岁,平均54.91岁。结果本组33例,治愈26例,死亡7例。行非手术治疗26例,死亡6例;行手术治疗7例,死亡1例。休克和多器官功能衰竭(MOF)是主要死亡原因。结论早期处理是治疗成功的第一个关键,控制感染是处理的另一个关键。继发明显感染、胆道梗阻时,应及时手术治疗,手术方式尽量简化。 Objective To strengthen the understanding of severe acute pancreatitis (SAP) and summarize the experience of treatment of severe acute pancreatitis. Methods The clinical data of 33 cases of severe acute pancreatitis admitted from 2003 to 2005 were retrospectively analyzed. Including 25 males and 8 females, aged 22 to 85 years, an average of 54.91 years old. Results The group of 33 cases, 26 cases were cured, 7 died. Non-surgical treatment of 26 cases, 6 patients died; surgery in 7 cases, 1 patient died. Shock and multiple organ failure (MOF) are the leading causes of death. Conclusion Early treatment is the first key to successful treatment and controlling infection is another key element in treatment. Obvious secondary infection, biliary obstruction, surgical treatment should be promptly, the surgical approach to simplify.