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NOISH发表了《当前病情报告》,提醒工人接触的一些有机溶剂具有一定的神经毒性。急性毒作用包括:麻醉、麻木、对中枢神经系统的抑制以及呼吸骤停、知觉丧失甚至死亡。常用有机溶剂分为直链烃、芳香烃、卤代烃、酮类、胺类、酯类、醇类、醛类和醚类。一般使用的溶剂多为上述溶剂的混合物。对接触有机溶剂工人的流行病学研究表明:周围神经功能发生慢性改变(感觉神经与运动神经的传导速度和肌电图的异常)。这种改变在停止接触后尚可持续数月甚至数年。流行病学调查还表明,长期接触有机溶剂对工人神经行为有显著影响。这些影响包括一些可逆性症状(疲劳、急躁和记忆力降低),性格、情绪的长期改变(情绪不稳定,自控能力降低及易发脾气)和智力受损(精力不易集中,记忆力及学习能力降低)。据
NOISH published the Current Disease Report, reminding workers that some organic solvents are neurotoxic. Acute toxic effects include: anesthesia, numbness, depression of the central nervous system and respiratory arrest, loss of consciousness and even death. Commonly used organic solvents into straight-chain hydrocarbons, aromatic hydrocarbons, halogenated hydrocarbons, ketones, amines, esters, alcohols, aldehydes and ethers. Most commonly used solvents are mixtures of the above solvents. Epidemiological studies of workers exposed to organic solvents show that peripheral nerve function changes chronically (sensory and motor nerve conduction velocity and EMG abnormalities). This change can persist for months or even years after the cessation of contact. Epidemiological investigations also show that prolonged exposure to organic solvents has a significant effect on workers’ neurological behavior. These effects include some reversible symptoms (fatigue, irritability and memory loss), long-term changes in personality and mood (emotional instability, reduced self-control and temper tantrums) and impaired intelligence (poor concentration, decreased memory and learning ability) . according to