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本文用明胶为囊材,将双氯灭痛包成微囊,并对微囊的主药含量、包囊率进行测定。然后把双氯灭痛微囊与维生素C、扑尔敏配伍制成复方双氯灭病微胶囊,对其稳定性、体外释放度、临床缓释效果考察等与感冒通片、维生素C银翘片进行研究,结果表明,双氯灭病微囊与胸溶片T50、Td比较具有显著差异(P<0.05)。复方双氯灭痛)、维生素C银翘片临床试验结果表明复方双氯灭病微囊具有明显缓释效果。
In this paper, gelatin as a capsule material, the diclofenac capsule into microcapsules, and the main drug content of microcapsules, cyst determination. Then diclofenac microcapsules and vitamin C, chlorpheniramine compatibility made of compound diclofenac microcapsules, its stability, in vitro release, the study of clinical sustained release effect and the cold pass, vitamin C Yinqiao tablets research The results showed that there was a significant difference (P <0.05) between diclofenac microcapsules and thoracic tablets T50 and Td. Compound diclofenac), vitamin C Yinqiao tablets clinical trial results show that the compound diclofenac microcapsules with a sustained release effect.