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目的:探究PTU对妊娠合并甲状腺功能亢进孕妇甲状腺功能及妊娠结局的影响。方法:选取我院2012年1月至2014年12月妇产科收治的妊娠合并甲亢患者68例进行研究。将其随机分为研究组和对照组各34例。对照组由于个人因素未使用PTU进行治疗,治疗组口服适量PTU进行治疗。结果:治疗后,治疗组患者的甲状腺TSH、TT3、FT4、FT3、TT4等各功能指标优于对照组,差异具有统计学意义(P<0.05)。两组产妇新生儿结局比较,差异具有统计学意义(P<0.05)。结论:准确的PTU治疗妊娠合并甲状腺功能亢进孕妇能有效改善甲状腺功能并得到较满意的妊娠结局,相对安全有效。
Objective: To investigate the effect of PTU on thyroid function and pregnancy outcome in pregnant women with hyperthyroidism. Methods: From January 2012 to December 2014 in our hospital, obstetrics and gynecology admitted 68 patients with hyperthyroidism during pregnancy were studied. They were randomly divided into study group and control group, 34 cases each. The control group did not use PTU for personal reasons, and the treatment group was orally administered with appropriate amount of PTU. Results: After treatment, the thyroid function indexes such as TSH, TT3, FT4, FT3 and TT4 in the treatment group were better than those in the control group, with statistical significance (P <0.05). The two groups of newborns maternal outcomes, the difference was statistically significant (P <0.05). Conclusion: Accurate PTU treatment of pregnant women with hyperthyroidism in pregnant women can effectively improve thyroid function and get more satisfactory pregnancy outcomes, relatively safe and effective.