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目的:评估非糜烂性胃食管反流病患者的焦虑、抑郁状态,分析其对生活质量的影响,探讨治疗的有效方案。方法:特地选取我院于2014年1月至2015年12月收治的非糜烂性胃食管反流病患者60例作为观察组,另选同时间段内来我院接受身体检查的患者60例作为对照组;利用汉密顿焦虑、抑郁自评量表评估两组患者的抑郁、焦虑状态,比较两组患者的生活质量。将观察组患者按照治疗方案的不同分为单一组和联合组。单一组仅用奥美拉唑进行治疗,而联合组采用黛力新联合奥美拉唑治疗,比较治疗后两组患者的情绪状态。结果:观察组患者的抑郁、焦虑得分明显高于对照组,生活质量得分明显低于对照组,生活质量与抑郁、焦虑状态明显的正性相关关系;而观察组经治疗后抑郁、焦虑状态及生活质量均得到明显改善,联合组的治疗效果明显好于单一组,两组间差异明显P<0.05有统计学意义。结论:非糜烂性胃食管反流患者常伴有不同程度的抑郁、焦虑状态,严重影响生活质量,而利用黛力新联合奥美拉唑治疗取得显著效果,临床应用价值高。
Objective: To evaluate the anxiety and depression status of patients with non-erosive gastroesophageal reflux disease and analyze their impact on quality of life, and to explore effective treatment options. Methods: Sixty patients with non-erosive gastroesophageal reflux disease who were treated in our hospital from January 2014 to December 2015 were selected as the observation group, and 60 patients who received physical examination in our hospital during the same period Control group. The Hamilton anxiety and depression self-rating scale were used to evaluate the depression and anxiety status of the two groups of patients and the quality of life was compared between the two groups. Patients in the observation group were divided into a single group and a combined group according to the treatment plan. The single group was treated with omeprazole only, while the combination group was treated with deaceticate and omeprazole, and the emotional status of the two groups was compared. Results: The depression and anxiety scores of the observation group were significantly higher than those of the control group, the quality of life scores were significantly lower than those of the control group, the quality of life was significantly positive correlation with depression and anxiety; while the observation group depression, anxiety and Quality of life were significantly improved, the treatment effect of the combination group was significantly better than a single group, the difference between the two groups was significantly P <0.05 statistically significant. Conclusion: Non-erosive gastroesophageal reflux patients are often accompanied by different degrees of depression and anxiety, which seriously affect the quality of life. However, the combination of dextromethorphan and omeprazole has achieved remarkable results and has high clinical value.