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目的总结甲状腺功能亢进患者病发的原因,探讨抗甲状腺药物治疗甲状腺功能亢进的临床疗效。方法甲状腺功能亢进患者34例,根据就诊单双号分为观察组和对照组,各17例。其中对照组实施单纯保肝治疗,观察组在保肝治疗基础上给予抗甲状腺药物进行配合治疗。观察分析两组患者临床治疗效果。结果通过实施不同方法治疗后,两组患者肝功能检查发现,血清总胆红素(TB)、直接胆红素(DB)差异具有统计学意义(P<0.05);丙氨酸氨基转移酶(ALT)、门冬氨酸氨基转移酶(AST)、白蛋白(ALB)、碱性磷酸酶(ALP)差异无统计学意义(P>0.05)。结论甲状腺功能亢进病发原因与自身睡眠、精神状况相关,在保肝治疗基础上给予抗甲状腺药物进行配合治疗疗效显著。
Objective To summarize the causes of the onset of hyperthyroidism and to explore the clinical efficacy of anti-thyroid drugs in the treatment of hyperthyroidism. Methods Thirty-four patients with hyperthyroidism were divided into two groups: observation group and control group, 17 cases in each group. Among them, the control group was treated with pure liver protection, and the observation group was treated with antithyroid drugs on the basis of liver protection treatment. Observation and analysis of two groups of patients with clinical treatment. Results After the treatment of different methods, liver function tests showed that there were significant differences in serum total bilirubin (TB) and direct bilirubin (DB) (P <0.05); alanine aminotransferase ALT, AST, ALB and ALP had no significant difference (P> 0.05). Conclusions The causes of hyperthyroidism are related to their own sleep and mental status. The treatment with anti-thyroid drugs on the basis of hepatoprotective therapy has a significant effect.