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间充质干细胞(MSCs)是主要来源于中胚层的多能干细胞,具有来源广泛、易于获得、低免疫原性、多向分化潜能、损伤修复、营养神经等特点和功能,广泛应用于多种疾病的临床治疗.近年国内外学者对MSCs各种生理特点的研究不断深入,并且把MSCs应用于视网膜疾病的治疗.本文就MSCs的免疫特点,如免疫标记、免疫调节特性、营养作用,以及MSCs对糖尿病视网膜病变(DR)、视网膜退行性疾病、脉络膜新生血管(CNV)、视网膜缺血-再灌注的免疫调节应用进行综述.“,”Mesenchymal stem cells (MSCs) derive mainly from the mesoderm pluripotent stem cells,with wide variety of sources,easily accessible,low immunogenicity,pluripotent,various damage repair,nutrition,and other features and functions.MSCs are widely used for clinical treatment of various diseases.In recent years,scholars deepens various physiological characteristics of MSCs,and the MSCs have been used in the treatment of retinal diseases.In this paper,the characteristics of the MSCs,such as immune markers,immunomodulatory properties,the role of nutrition and MSCs immune on diabetic retinopathy (DR),retinal degenerative diseases,choroidal neovascular (CNV),retinal ischemia-reperfusion immunomodulatory applications were reviewed.