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目的探讨小儿急性链球菌感染后肾小球肾炎并发全心扩大的临床表现及治疗方法。方法回顾性分析2012年5月—2013年5月我院收治的25例急性链球菌感染后肾小球肾炎并发全心扩大患儿的临床资料,记录治疗方法和效果。结果本组25例患儿在经过积极治疗后均在24 h内明显好转,心脏循环充血症状得到控制。治疗后患儿发热、轻咳、咽痛、脓疱疹、水肿及呼吸急促所占比例均低于治疗前(P<0.05)。患儿住院时间为10~25 d,平均(12.3±5.1)d。治疗后患儿心脏扩大程度优于治疗前(P<0.05)。结论小儿急性链球菌感染后肾小球肾炎并发全心扩大主要临床表现为发热、轻咳、咽痛、脓疱疹、水肿及呼吸急促,综合分析临床症状,结合仪器检查可以帮助医生尽早确定病情,积极对症治疗,提高抢救成功率。
Objective To investigate the clinical manifestations and treatment of glomerulonephritis complicated with enlarged heart after acute streptococcal infection in children. Methods A retrospective analysis of 25 cases of acute streptococcal glomerulonephritis admitted to our hospital from May 2012 to May 2013 in our hospital was performed. The clinical data of children with enlarged heart were retrospectively analyzed. The treatment methods and effects were recorded. Results 25 patients in this group after active treatment were significantly improved within 24 h, congestive heart symptoms under control. After treatment, children with fever, light cough, sore throat, impetigo, edema and shortness of breath were lower than before treatment (P <0.05). Children hospitalized for 10 ~ 25 d, with an average (12.3 ± 5.1) d. After treatment, the degree of heart enlargement in children was better than that before treatment (P <0.05). Conclusions The main clinical manifestations of glomerulonephritis complicated with acute glomerulonephritis complicated with acute streptococcal infection are fever, light cough, sore throat, impetigo, edema and shortness of breath. Comprehensive analysis of clinical symptoms combined with instrumental examination can help doctors to confirm the condition as soon as possible, Positive symptomatic treatment and improve the success rate of rescue.