近年来的研究表明 ,人类免疫缺陷病毒 (ＨＩＶ)易感基因ＣＣＲ5、ＣＣＲ2和ＳＤＦ1等基因位点的突变可干扰艾滋病的发病进程[1,2 ] 。其中ＣＣＲ5 △ 32基因突变似乎是最重要的因素 ,它的纯合子突变可降低ＨＩＶ传播的危险性 ,杂合子突变可以延缓艾滋病的发病进程 ,ＣＣＲ2 6 In recent years, studies have shown that mutations in the human immunodeficiency virus (HIV) susceptibility genes CCR5, CCR2 and SDF1 may interfere with the pathogenesis of AIDS [1,2]. Among them, CCR5 △ 32 gene mutation seems to be the most important factor, its homozygous mutation can reduce the risk of HIV transmission, heterozygous mutation can delay the onset of AIDS, CCR26