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目的:探析基于“互联网＋”的手机app在2型糖尿病(T2DM)患者管理中的应用效果。方法:以2018年11~12月在清远市人民医院内分泌科诊治并建档的T2DM患者120例纳入实践观察中，基于随机数字表法分成试验组和对照组各60例，均行专科对症治疗。对照组采取常规随访管理，试验组同时应用健康管理手机app，持续12个月。比较分析两组干预前后空腹血糖(FBG)、餐后2 h血糖(2 hBG)、糖化血红蛋白(HbA1c)、血压及体重指数(BMI)变化，并通过问卷评测患者健康知识知晓率和健康行为执行情况。结果:干预前两组患者FBG、2 hBG、HbA1c、血压及BMI差异均无统计学意义(均n P>0.05)，干预后试验组均显著优于对照组，差异有统计学意义(均n P<0.05)。通过问卷评测，试验组患者的健康知识知晓率为96.67%，遵医用药率为96%，饮食控制率93.33%，坚持运动率为88.33%，对照组分别为85.00%、85.00%、80.00%、76.67%，差异有统计学意义(n P0.05), while after intervention, the experimental group was significantly better than the control group, and the difference was statistically significant (n P<0.05). Questionnaire evaluation results showed that the rate of health knowledge awareness, compliance with medical drugs, diet control rate and exercise adherence rate of patients in the experimental group were 96.67%, 96.00%, 93.33% and 88.33%, respectively, while those in the control group were 85.00%, 85.00%, 80.00% and 76.67%, respectively, and the differences were statistically significant(n P<0.05).n Conclusions:The application of “ Internet + ” app in the health management of T2DM patients can effectively enhance the blood glucose level and quality control effect, improve the health cognition of patients, and strengthen the executive ability of health behaviors.