脱钙骨移植是Senn于1889年首先报导的。他把牛的胫骨在稀盐酸中脱钙后贮存在1∶500的升汞酒精溶液中,用这种储存骨修复狗的颅骨缺损和胫骨骨腔获得成功,并用于10例患者,移植充填骨髓炎搔刮术后所致之骨腔,效果良好。后来学者们逐渐发现临床应用脱钙牛骨失败和吸收率很高,在动物实验中,异体脱钙骨移植效果更好。Ray(1957)、Heiple(1963)、Frcibery(1964)等实验证明异体脱钙骨移植后比异体冷冻骨、异体脱蛋白骨、异体新鲜骨以 Decalcified bone graft was first reported by Senn in 1889. He decalcified bovine tibia in dilute hydrochloric acid and stored in a 1: 500 aliquot of mercapto-alcoholic solution. The bones were used to repair the skull defect and the tibial cavity of the dog, and were used in 10 patients with transplanted bone marrow Inflammation curettage caused by the bone cavity, the effect is good. Later, scholars gradually found that clinical application of decalcified bovine failure and high absorption rate, in animal experiments, allograft bone transplantation better. Ray (1957), Heiple (1963), Frcibery (1964) and other experiments show that allograft bone than after allogeneic frozen bone, allogeneic deproteinized bone, allogeneic fresh bone to