自然杀伤细胞 (naturalkillercell,NK)是无需预先致敏 ,无MHC限制性 ,能直接杀伤靶细胞的一类特殊的淋巴细胞群体 ,由于NK细胞在抗感染和抗肿瘤中起着重要作用而成为近来肿瘤生物治疗的研究热点。NK细胞系的建立尤其是NK 92的建立促进了其在肿瘤过继免疫治疗中的应用研究 ,并为深入研究NK细胞的特征、功能 ,进一步揭示它在免疫系统中的确切作用 ,提供了更为有利的研究材料和方法 Natural killer cell (NK), a kind of special lymphocyte population that can directly kill target cells without pre-sensitization and without MHC restriction, has recently become a new type of NK cell because of its important role in anti-infective and anti-tumor Cancer biotherapy research hot spots. The establishment of NK cell line, especially the establishment of NK 92, has promoted its application in adoptive immunotherapy of tumors. In order to further study the characteristics and functions of NK cells and further reveal its exact role in the immune system, Favorable research materials and methods