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目的 :了解前白蛋白 ( PA)在白血病细胞肝浸润诊断中的意义。方法 :对 3 3例患儿在治前及完全缓解后的 2 4例患儿和 3 0例健康儿童对照组 ,通过免疫比浊法测定 PA,并检测其它肝功能值。结果 :3 3例患儿治疗前 ,11例 PA下降 ,3例白蛋白降低 ,3例谷丙转氨酶、9例谷草转氨酶升高 ,1例总胆红素上升 ,治前 PA异常的例数高于肝功能其它值异常的例数。其中经治疗完全缓解后的 2 4例患儿 ,PA及肝功能其它值则均在正常范围。结论 :治前白血病对肝浸润时、PA的变化较肝功能其它值的变化为明显
Objective: To understand the significance of prealbumin (PA) in the diagnosis of hepatic infiltration in leukemia cells. Methods: Twenty-three children with congenital or complete remission and 30 normal children were enrolled in this study. PA was measured by immunoturbidimetry and other liver function values were measured. Results: Before treatment, 11 cases of PA decreased, 3 cases of albumin decreased, 3 cases of alanine aminotransferase, 9 cases of aspartate aminotransferase increased, and 1 case of total bilirubin increased. The number of PA abnormalities before treatment was high The number of abnormal liver function in other cases. Among them, 24 cases of complete remission after treatment, PA and other liver function values were in the normal range. Conclusions: When pre-treatment leukemia is infiltrated with liver, the change of PA is more obvious than other values of liver function