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本文采用有机泡沫浸渍结合无压烧结制备了多孔HAP-(β-Ca3(PO4)2)-S i3N4生物复合材料,采用静态血小板浸渍实验研究了所制备多孔生物复合材料的血液相容性。复合材料的表面形态对血小板的沉积有一定影响,孔隙越大、表面越粗糙,血小板越容易沉积。发现在不同成分的复合材料表面,在血小板的粘附、聚集状态方面无明显的差异,其表面大部分区域无血小板粘附,有少部分区域有少量纤维蛋白沉积。表明复合材料具有良好的血液相容性,作为支架材料不会引起凝血现象。
In this paper, porous HAP- (β-Ca3 (PO4) 2) -Si3N4 composites were prepared by organic foam impregnation combined with pressureless sintering. The blood compatibility of the prepared porous bio-composites was investigated by static platelet immersion experiments. The surface morphology of composite materials has certain influence on the deposition of platelets. The larger the pore size, the rougher the surface, the easier the deposition of platelets. It was found that there was no significant difference in the adhesion and aggregation of platelets on the surface of composite materials with different compositions. There was no platelet adhesion in most of the surface of the composite, and a small amount of fibrin deposition in a few areas. Show that the composite has good blood compatibility, as a scaffold material will not cause coagulation phenomenon.