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目的应用超声心动图技术检测左心房功能指数,以评价高血压患者的左心房功能变化。方法选择60例高血压患者和31例健康对照者,记录身高、体重,常规测量左心房内径(LAD)、左心室流出道血流的速度时间积分(LVOT-VTI),采用双平面法测量左心房最大容积(LAESV)、左心房射血分数(LAEF),计算左心房搏出量(LASV)及左心房功能指数(LAFI),利用组织多普勒测量二尖瓣环运动频谱(Ea、Aa),并且计算Ea/Aa比值。结果高血压患者的LAFI较健康对照者降低(0.53±0.19 vs.0.79±0.23,P<0.05),高血压组内LAD增大者的LAFI较LAD正常范围者降低(0.47±0.18 vs.0.58±0.18,P<0.05);LAFI与Ea、Aa、Ea/Aa、LAD、LASV、LAEF进行相关性分析,结果示LAFI与Ea(r=0.43,P<0.001)、Ea/Aa(r=0.29,P<0.005)、LAEF(r=0.59,P<0.001)呈正相关,与LAD(r=-0.53,P<0.001)、LASV(r=-0.49,P<0.001)呈负相关。结论高血压患者LAFI减低,LAFI是评价左心房功能变化有意义的指标。
Objective To evaluate left atrial function index by echocardiography to evaluate left atrial function in hypertensive patients. Methods Sixty hypertensive patients and 31 healthy controls were selected. The height and weight, the left ventricular diameter (LAD) and the left ventricular outflow tract velocity time integral (LVOT-VTI) were recorded. The biplane method was used to measure the left (LAESV) and left atrial ejection fraction (LAEF), left atrial stroke volume (LASV) and left atrial function index (LAFI) were calculated. Tissue Doppler was used to measure mitral annular motion spectrum (Ea, Aa ), And calculate the Ea / Aa ratio. Results The LAFI of hypertensive patients was lower than that of healthy controls (0.53 ± 0.19 vs.0.79 ± 0.23, P <0.05). The LAFI of hypertensive patients with increased LAD was lower than that of normal LAD (0.47 ± 0.18 vs.0.58 ± (R = 0.43, P <0.001), Ea / Aa (r = 0.29, P <0.05). The correlation between LAFI and Ea, Aa, Ea / Aa, LAD, LASV, (P <0.001). There was a positive correlation between LAEF (r = -0.53, P <0.001) and LASV (r = -0.49, P <0.001) Conclusions LAFI is decreased in patients with hypertension, and LAFI is a meaningful index for evaluating left atrial function.