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目的观察胆囊结石合并胆总管结石双镜微创与开腹手术的临床治疗效果.方法选取2010年5月—2013年2月间入我院进行治疗的胆囊结石合并胆总管结石患者60例为研究对象,随机分为对照组和研究组,分别实施开腹手术和腹腔镜联合十二指肠镜双镜微创手术治疗,观察手术情况、治疗效果和并发生发生情况.结果双镜联合治疗组出血量和住院天数均少于开腹手术组,手术时间大于开腹组,差异具有统计学意义(P <0.05).双镜联合手术组残余结石和切口感染发生率低于开腹手术组,高淀粉酶血症、胆总管下端炎性狭窄发病率高于对照组,差异具有统计学意义(P <0.05).结论胆囊结石合并胆总管结石双镜微创手术治疗效果较好,临床应用价值高.“,”Objective To observe the clinical effect of the treatment of cholecystolithiasis and choledocholithiasis double mirror minimaly invasive operation and laparotomy. Methods from 2010 May to 2013 February in our hospital between patients with cholecystolithiasis and choledocholithiasis therapy in 60 patients as the research object, randomly divided into the study group and the control group, respectively, the implementation of open operation and laparoscopy union duodenoscopy double mirror minimaly invasive operation treatment, to observe the operation situation, treatment effect and occurrence condition. Results two mirror combined treatment group, bleeding and hospitalization were less than open operation group, operation time is greater than the open group, the difference was statisticaly significant (P ﹤ 0.05). Endoscopy combined operation group of residual stones and the incision infection rate is lower than the open operation group, hyperamylasemia, bile duct stricture incidence was higher than that of the control group, the difference was statisticaly significant (P ﹤ 0.05). To investigate the effects of dual mirror minimaly invasive operation conclusion cholecystolithiasis and choledocholithiasis, clinical application.