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目的:评价阿泰宁联合美沙拉嗪治疗溃疡性结肠炎临床疗效。方法:对照组25例只给予美沙拉嗪(0.5 g,3次/d),治疗12周。治疗组25例给予阿泰宁(1 260 mg,2次/d)和美沙拉嗪(0.5 g,3次/d),治疗12周。分别统计两组治愈、显效、有效、无效病例数以及总有效率,并对两组总有效率进行样本均数比较的u检验。结果:对照组治愈9例,显效6例,有效4例,无效6例,总有效率为76%。治疗组治愈17例,显效5例,有效2例,无效1例,总有效率为96%。对两组总有效率进行样本均数比较的u检验(P<0.05)。结论:阿泰宁联合应用美沙拉嗪比单独应用美沙拉嗪治疗轻中度溃疡性结肠炎更具有临床疗效。
Objective: To evaluate the clinical efficacy of Artenin combined with mesalazine in the treatment of ulcerative colitis. Methods: 25 cases in the control group were treated with Mesalazine (0.5 g, 3 times daily) for 12 weeks. Twenty-five patients in the treatment group were treated with atenolol (1,260 mg twice a day) and mesalazine (0.5 g three times a day) for 12 weeks. The two groups were statistically cured, effective, effective, invalid cases and the total effective rate, and the total effective rate of the two groups of samples were compared u test. Results: In the control group, 9 cases were cured, 6 cases were markedly effective, 4 cases were effective and 6 cases were ineffective. The total effective rate was 76%. Treatment group cured 17 cases, markedly effective in 5 cases, effective in 2 cases, ineffective in 1 case, the total effective rate was 96%. The two groups were compared for the total efficiency of the sample mean u test (P <0.05). CONCLUSION: Artainine combined with mesalazine has more clinical efficacy than mesalazine alone in the treatment of mild to moderate ulcerative colitis.