论文部分内容阅读
以己烯雌酚皮下注射每只小鼠０．２ ｍ ｇ／（次·ｄ），连续注射３ ｄ，第４ ｄ 实验前分别灌胃给药（０．２ ｍ ｌ／１０ ｇ 小鼠），药后３０ ｍ ｉｎ 腹腔注射催产素０．２ ｕ／只，造成小鼠“痛经”模型，分别观察３ 种不同剂量的九气拈痛胶囊对小鼠“痛经”模型潜伏期、扭体次数及扭体发生率， 与模型空白组比较分别具有非常显著性意义（Ｐ＜ ０．０５、０．０１）；同时还发现胶囊大、中剂量组优于原剂型组（九气拈痛丸）及阳性对照组，说明本品对痛经具有较好的治疗作用。
Diethylstilbestrol was injected subcutaneously into each mouse at a dose of 0.2 mg/(day·d) for 3 days, and then administered intragastrically (0.2 ml/10 g mouse) before the 4th day of the experiment. 30 m in intraperitoneal injection of oxytocin 0.2 u/only resulted in a mouse model of dysmenorrhea. Observed three different doses of Jiuqi Qutong capsules in the mouse model of dysmenorrhea, incubation period, writhing frequency and writhing The rate was significantly different from that of the blank group (P<0.05, 0.01). At the same time, it was also found that capsules in the large and middle dose groups were superior to the original formulation group (Jiu Qi Futong Pills) and the positive control group. This shows that this product has a good therapeutic effect on dysmenorrhea.