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作者对1980～1990年间在Sloan-Ketlering纪念医院接受保守性手术加放射治疗的558例早期浸润性乳腺癌病例进行了回顾性分析,其目的是确定影响老年乳腺癌治疗决策的因素和由此带来的疗效差异。根据年龄将患者分为<65岁(432例)和≥65岁(126例)两组,除老年组中未作腋淋巴结清扫(Nx期者占20.6％)而年轻组中只有5.3％外,两组病例的TNM分期相似。统计学分析表明,两组病人的总的生存率和无瘤生存率无差异,但是老年组的5年和10年的局部控制率均高于年轻组(P=0.01),并且老年
The authors retrospectively analyzed 558 cases of early invasive breast cancer undergoing conservative surgery plus radiotherapy at the Sloan-Ketlering Memorial Hospital between 1980 and 1990. The purpose of this study was to determine the factors that influence the decision-making for the treatment of elderly breast cancer and the The difference in efficacy. According to age, the patients were divided into two groups: <65 years old (432 cases) and ≥65 years old (126 cases), except for the elderly group who did not undergo axillary lymph node dissection (20.6% in Nx stage) but only 5.3% in the young group. TNM staging was similar in both groups. Statistical analysis showed that the overall survival rate and disease-free survival rate of the two groups were not different, but the 5-year and 10-year local control rates of the elderly group were higher than the young group (P=0.01), and the elderly