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目的:探讨卵巢支持-间质细胞肿瘤的临床、病理特征、治疗和预后。方法:回顾性分析我院10年来3例卵巢支持-间质细胞肿瘤的临床及病理资料。结果:3例患者中,1例患者有闭经及高雄表现,1例闭经、盆腔肿物蒂扭转、下腹痛表现,1例仅B超提示盆腔肿物。3例患者中,病理分化程度:1例为中度分化及分化不良,1例为高分化,1例我院病理提示符合性索间质肿瘤,倾向于卵巢支持-间质细胞肿瘤,低度恶性,后经中科院肿瘤医院会诊病理报告单:(卵巢)免疫组化结果首先提示性索间质肿瘤(瘤细胞巢大部分有挤压),形态较特殊且不典型,不能具体分类。3例患者均以手术治疗为主,2例已生育,患者行患侧附件切除术,1例未生育患者仅行患侧卵巢肿物剥除术。经随访1.5-3年未见异常。结论:卵巢支持-间质细胞肿瘤治疗以手术为主。根据患者的年龄,生育要求,临床分期,分化程度以及肿瘤有无破裂来确定手术范围。
Objective: To investigate the clinical, pathological features, treatment and prognosis of ovarian support-stromal tumor. Methods: The clinical and pathological data of 3 cases of ovarian support-stromal tumor in our hospital over 10 years were retrospectively analyzed. Results: Of the 3 patients, 1 patient had amenorrhea and Kaohsiung, 1 had amenorrhea, had pelvic pedicle torsion and lower abdominal pain, and 1 patient had only B-ultrasound suggestive of pelvic mass. Among the 3 patients, the pathological grade was 1 case of moderately differentiated and poorly differentiated, 1 case of well differentiated, 1 case of pathological findings in our hospital were consistent with stromal tumors, favoring ovarian support - stromal cell tumors, low Malignant, after the Chinese Academy of Sciences Cancer Hospital consultation pathology report: (ovarian) immunohistochemistry results first prompted prominence stromal tumors (most of the tumor nests have squeezed), the shape of a more specific and atypical, can not be specific classification. Three patients were treated by surgery, two patients had fertility, and the patients underwent resection of the ipsilateral appendages. One patient who did not give birth had only ipsilateral ovarian tumor stripping. After follow-up 1.5-3 years without exception. CONCLUSIONS: Ovarian support - stromal tumor treatment is dominated by surgery. According to the patient’s age, fertility requirements, clinical stage, degree of differentiation and tumor rupture to determine the scope of the operation.