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目的:运用似然比(LR)定量评价孤立性肺结节(SPN)相关的各种临床表现和CT特征在其定性诊断中的价值。方法:经手术病理或临床确诊的SPN病例352例(恶性135例,良性217例),分别统计各临床和CT表现在恶性和良性SPN中的出现率,计算两者的比值即似然比(LR)。结果:较能提示恶性SPN的特征为空泡征(LR=4.98)、短毛刺(LR=4.57)、深分叶(LR=3.88)等,较能提示良性SPN的特征为良性钙化模式(LR=0.03)、强化值<20HU(LR=0.08)、多边形轮廓(LR=0.14)等。结论:似然比能为医生准确权重各临床和CT表现在SPN定性诊断中的意义提供参考,可以用来指导日常阅片。
Objective: To evaluate the clinical value and CT features of solitary pulmonary nodules (SPNs) quantitatively in the qualitative diagnosis by using the likelihood ratio (LR). Methods: A total of 352 SPN cases (135 malignant and 217 benign) were confirmed by pathology or clinical diagnosis. The incidences of clinical and CT findings in malignant and benign SPN were respectively calculated. The odds ratio LR). Results: It is suggested that malignant SPN is characterized by vacuolar sign (LR = 4.98), short burr (LR = 4.57) and deep lobulation (LR = 3.88) = 0.03), fortified value <20HU (LR = 0.08), polygon outline (LR = 0.14) and so on. Conclusion: Likelihood ratio can provide a reference for the clinicians and CT findings in the qualitative diagnosis of SPN, which can be used to guide daily reading.