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Ｔ细胞产生的细胞因子可分为Ｔｈ_１和Ｔｈ_２两大类。Ｔｈ_１类细胞因子包括ＩＬ－２、ＩＦＮ_（－γ）等，主要介导细胞免疫反应，在胞内寄生菌、原虫或病毒感染中起保护作用，但也参与自身免疫及某些慢性炎症性疾病的免疫病理过程。Ｔｈ_２类细胞因子包括ＩＬ－４、ＩＬ－５等，主要介导体液免疫反应，在蠕虫感染中起保护作用，但在特应性个体可触发变态反应性疾病。此外，Ｔｈ_２类细胞因子对Ｔｈ_１类的抑制作用虽然可减轻Ｔｈ_１类细胞因子介导的免疫病理损伤，但同时因削弱细胞免疫反应而致疾病的发展。
The cytokines produced by T cells can be divided into Th1 and Th2 two categories. Th_1 cytokines, including IL-2, IFN_ (-), etc., mainly mediate cellular immune responses and play a protective role in intracellular parasites, protozoa or viral infections but are also involved in autoimmunity and certain chronic inflammatory diseases The immune pathology process. Th2 cytokines, including IL-4, IL-5, etc., mainly mediate humoral immune responses and play a protective role in helminth infection, but can trigger allergic diseases in atopic individuals. In addition, although the inhibitory effect of Th2-like cytokines on the Thl-like cells may reduce the immunopathological damage induced by Thl-like cytokines, it may also lead to the development of diseases by impairing the cellular immune response.