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目的对本院质子泵抑制剂的使用情况进行分析,为临床合理、经济高效地使用药物提供参考依据。方法对本院2006～2008年质子泵抑制剂的用药频度(DDDs)、总消耗金额、日治疗费用进行统计,分析。结果奥美使用频率居调查药品中最高,且呈明显上升趋势,平均增幅为162.2%。耐信(20mg)的DDDs排在第二位。DDDs相对靠后的多为药物疗效差异不大,价格偏高的药物,如兰索拉唑(臣邦力威)。奥美的金额序号/DDDs序号的序号比为4.00,序号比最大,表明该药的使用频度较高,但其日治疗费用却相对较低。雷贝拉唑钠肠溶片(安斯菲)的排序比值小于0.5,说明其价格偏高。结论质子泵抑制剂的使用数量和频率呈快速上升状态,表明近年来人们的胃部疾病不断增加,所耗费的治疗金额不断增加。
Objective To analyze the use of proton pump inhibitors in our hospital and provide reference for clinical use of drugs in a rational and cost-effective manner. Methods The frequency of drug use (DDDs), the total cost and the cost of daily treatment of proton pump inhibitors in our hospital from 2006 to 2008 were statistically analyzed. Results Ogilvy used the highest frequency among the investigated drugs with a marked upward trend, with an average increase of 162.2%. Durable (20mg) DDDs came in second place. DDDs relatively much later, mostly for the difference in drug efficacy, high prices of drugs, such as lansoprazole (Chen Bangli Viagra). Ogilvy’s serial number / DDDs serial number ratio of 4.00, the highest serial number, indicating that the drug is used more frequently, but its treatment costs are relatively low. Rabeprazole sodium enteric-coated tablets (Anfite) sorting ratio of less than 0.5, indicating that the high price. Conclusions The number and frequency of use of proton pump inhibitors showed a rapid increase, indicating that in recent years, people’s stomach diseases have been increasing and the amount of treatment cost has been on the increase.