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目的探讨血液灌流治疗高脂血症性急性胰腺炎的疗效。方法患者均是2012年1月—2014年2月收治的高脂血症性急性胰腺炎患者,对照组12例,血液灌流组14例,对照组给予中西医结合治疗,血液灌流组在对照组的基础之上加用血液灌流治疗。观察治疗前后甘油三酯水平、氧合指数、腹痛、腹胀缓解时间及住院时间。计量资料采用t检验,P<0.05为差异有统计学意义。结果入院24、48 h血液灌流组血清甘油三酯[(14.32±3.57)、(5.66±1.67)mmol/L]均明显低于对照组(均P>0.05),入院48 h血液灌流组氧合指数[(287.33±27.28)mm Hg(1 mm Hg=0.133 kPa)]均明显低于对照组(均P>0.05)。与对照组相比,血液灌流组患者腹痛、腹胀消失时间、住院时间[(2.3±1.2)、(3.3±1.5)、(14.0±4.0)d]差异均有统计学意义(均P<0.05)。结论血液灌流治疗高脂血症性急性胰腺炎效果满意,值得临床应用。
Objective To investigate the therapeutic effect of hemoperfusion on hyperlipidemic acute pancreatitis. Methods The patients were all patients with hyperlipidemic acute pancreatitis who were admitted from January 2012 to February 2014, 12 cases in the control group and 14 cases in the hemoperfusion group. The control group was treated with the combination of TCM and Western medicine. In the control group Based on the plus hemoperfusion treatment. Before and after treatment, triglyceride level, oxygenation index, abdominal pain, abdominal distension time and hospital stay were observed. Measurement data using t test, P <0.05 for the difference was statistically significant. Results Serum triglycerides in hemoperfusion group (14.32 ± 3.57) and (5.66 ± 1.67) mmol / L at 24 and 48 h after admission were significantly lower than those in control group (all P> 0.05) Index [(287.33 ± 27.28) mm Hg (1 mm Hg = 0.133 kPa)] were significantly lower than those in the control group (all P> 0.05). Compared with the control group, there were significant differences in abdominal pain, disappearance of abdominal distension, length of stay in hospital [(2.3 ± 1.2), (3.3 ± 1.5), (14.0 ± 4.0) d] in the hemoperfusion group (all P <0.05) . Conclusion Hemoperfusion treatment of hyperlipidemic acute pancreatitis with satisfactory results, it is worth clinical application.