围生儿预防接种的有效性与安全性分析

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目的分析围生儿预防接种的有效性与安全性。方法回顾性分析702例实施预防接种的围生儿的临床资料,对所出现的常见不良反应进行统计,并对实施针对性治疗举措,分析其有效性和安全性。结果 702例接受预防接种的围生儿当中,37例围生儿出现不良反应症状,其不良反应发生率为5.27%。250例围生儿接种百白破三联疫苗围生儿不良反应为16例;65例接种脊髓灰质炎疫苗不良反应为1例;199例接种乙肝疫苗不良反应为9例;99例接种卡介苗预防结核病疫苗不良反应为7例;89例接种疫苗为麻疹疫苗不良反应为4例。不良反应表现为全身反应、局部反应、偶合反应及心因性反应等,对其进行针对性治疗举措,5 d内围生儿所存在不良反应均彻底消失,对所选取围生儿实施随访工作,未出现不良反应及其他形式严重状况。结论针对围生儿实施预防接种,其有可能发生不良反应状况,但是其总体有效性和安全性良好,针对不良反应状况采取相应治疗举措,不良反应均得以消失,保证围生儿正常发育。 Objective To analyze the effectiveness and safety of perinatal vaccination. Methods A retrospective analysis of 702 cases of perinatal vaccination implementation of clinical data on the occurrence of common adverse reactions statistics, and the implementation of targeted treatment initiatives, analysis of its effectiveness and safety. Results Among the 702 infants receiving immunization, 37 cases of perinatal children showed symptoms of adverse reactions with a rate of 5.27%. There were 16 cases of perinatal adverse reactions in 250 cases of perinatal inoculation diphtheria polyhedrosis vaccine; 65 cases of polio vaccine adverse reactions were in 1 case; 199 cases of hepatitis B vaccine adverse reactions in 9 cases; 99 cases of BCG vaccination prevention of tuberculosis The adverse reactions of the vaccine were 7 cases; the adverse reactions of 89 vaccines to measles vaccine were 4 cases. Adverse reactions manifested as systemic reactions, local reactions, coupling reactions and psychogenic reactions, the targeted treatment measures, 5 d of neonatal adverse reactions were completely disappeared, the selection of perinatal follow-up work carried out , No adverse reactions and other forms of serious condition. Conclusions Perinatal infant immunization may cause adverse reactions. However, its overall effectiveness and safety are good. Adopting corresponding treatment measures according to the adverse reactions, the adverse reactions disappear and the normal development of perinatal children is guaranteed.
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