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肝干细胞,又称肝卵圆细胞(hepatic oval cell, HOC),在体内可分化为肝细胞或胆管上皮细胞。目前HOC的分离和培养技术及干细胞移植技术已为肝病治疗带来了希望。本文主要就肝干细胞及其临床应用的最新研究进展作了综述。
Liver stem cells, also known as hepatic oval cells (HOCs), can differentiate into hepatocytes or biliary epithelial cells in vivo. The current HOC isolation and culture technology and stem cell transplantation technology has brought hope for the treatment of liver disease. This article mainly reviews the latest research progress of hepatic stem cells and its clinical application.