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目的了解呼吸科重症监护病区(RICU)和普通病区下呼吸道铜绿假单胞菌感染及耐药性,为临床防治提供依据。方法回顾性分析下呼吸道铜绿假单胞菌感染患者临床资料与药敏试验的结果。结果铜绿假单胞菌分离率为35.8%,其中RICU病区23.6%,普通病区为12.2%,RICU病区铜绿假单胞菌对多种抗生素的耐药性,明显高于普通病区(P<0.01)。结论铜绿假单胞菌仍然是呼吸病房下呼吸道感染最重要的致病菌,应根据不同病区合理选择抗生素。
Objective To understand the infection and drug resistance of Pseudomonas aeruginosa in the respiratory tract intensive care unit (RICU) and lower respiratory tract in general ward, and to provide basis for clinical prevention and treatment. Methods The clinical data and susceptibility testing results of patients with lower respiratory tract Pseudomonas aeruginosa infection were retrospectively analyzed. Results The isolation rate of Pseudomonas aeruginosa was 35.8%, of which 23.6% were in RICU and 12.2% in common disease. The resistance of Pseudomonas aeruginosa to various antibiotics in RICU was significantly higher than that in common disease P <0.01). Conclusion Pseudomonas aeruginosa is still the most important pathogenic bacteria in respiratory ward infection of lower respiratory tract. Antibiotics should be chosen according to different wards.