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氯乙烯(VC)的毒性作用,随着氯乙烯聚合工人中肝脏血管肉瘤发病率的增高而逐渐被重视。 在工业部门中VC的主要吸收途径是通过肺脏。虽然还没有资料证明人的皮肤有吸收作用,但是不能除外的是,己发现氯乙烯的化合物能渗入所接触的猴子的皮肤。Buchter等报告,VC在肺部的滞留率是26—28％,但这些结果仅从二名接触2.5PPm的VC人的体中得到,因此,很可能有误差。这次研究的目的,是要确定VC在人体肺部的滞留率。
The toxic effect of vinyl chloride (VC), with the polymerization of vinyl chloride workers increased the incidence of hepatic angiosarcoma and gradually attention. In the industrial sector, the main route of VC absorption is through the lungs. Although there is no evidence that human skin has an absorption effect, it can not be excluded that a vinyl chloride compound has been found to penetrate the skin of the contacted monkey. Buchter et al. Reported that the retention rate of VC in the lungs was 26-28%, but these results were only obtained from two individuals exposed to 2.5 PPm of VC, and as a result, there is a high possibility of error. The purpose of this study was to determine the retention rate of VC in human lungs.