论文部分内容阅读
目的 探讨住院患者并发深部白色念珠菌感染的危险因素。方法 通过回顾性调查对１９９５年１ 月～１９９７ 年１２ 月发生的４４ 例深部白色念珠菌感染患者的危险因素进行分析。结果 发生医院内部白色念珠菌感染多系慢性呼吸系统疾病、恶性肿瘤和血液病患者，占５９－０９ ％ ；感染与住院时间成正比；广谱抗生素大剂量、长时间应用，特别是选择广谱、杀菌力强的第三代头狍菌素类是致感染的主要因素；白色念珠菌感染是多种危险因素综合作用的结果，感染者使用激素的占４０－９１ ％ ，使用免疫抑制剂及放疗化疗的占１１－３６％ ，实施插入性操作及各种介入性治疗为感染创造了条件。结论 强调合理使用抗生素，严格控制免疫抑制剂的应用，合理掌握放疗化疗及各种诊疗技术，提高机体免疫力，是预防深部白色念珠菌感染的重要措施
Objective To explore the risk factors for deep C. albicans infection in hospitalized patients. METHODS: Risk factors for 44 patients with deep C. albicans infections from January 1995 to December 1997 were analyzed retrospectively. Results Hospital internal Candida albicans infections of chronic respiratory diseases, malignant tumors and hematological diseases accounted for 59-99%; infection and hospitalization time is proportional to; broad-spectrum antibiotics large doses, long-term application, especially the selection of broad-spectrum The third generation of cephaloplanin with strong bactericidal activity is the main cause of infection; Candida albicans infection is the result of a combination of various risk factors. The use of hormones accounts for 40-91% of infected persons, and the use of immunosuppressants and Radiotherapy and chemotherapy account for 11-36%, and insertional procedures and various interventional treatments have created conditions for infection. Conclusion Emphasis on the rational use of antibiotics, strict control of the application of immunosuppressive agents, reasonable control of radiotherapy and chemotherapy and various diagnostic and therapeutic techniques, and improvement of body immunity are important measures for the prevention of deep Candida albicans infection.