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为探讨Ⅱ型糖尿病患者血小板活化状态的变化规律。应用流式细胞免疫学技术对６３例 Ⅱ型糖尿病患者、 ５０例正常对照者血小板 ＣＤ６ｐ进行定量检测，并经统计处理。 Ⅱ型糖尿病患者血小板 ＣＤ６２ｐ表达量明显高于对照组（Ｐ＜ ０．０１），有血管并发症糖尿病患者 ＣＤ６２ｐ表达量显著高于无血管并发症组（Ｐ＜ ０．０１），且无血管并发症组 ＣＤ６２ｐ表达量亦显著高于对照组（Ｐ＜ ０．０１）。显示检测ＣＤ６２ｐ的表达量能预测糖尿病患者血小板活化状态，对防止糖尿病患者并发血管病变有重要意义。
To investigate the changes of platelet activation in patients with type 2 diabetes mellitus. Flow cytometry was used to quantitatively detect platelet CD6p in 63 patients with type 2 diabetes mellitus and 50 normal controls and the results were statistically analyzed. The expression of CD62p on platelet in type 2 diabetic patients was significantly higher than that in control group (P <0.01). The expression of CD62p in diabetic patients with vascular complications was significantly higher than that of non-diabetic patients (P <0.01) The expression of CD62p in disease group was also significantly higher than that in control group (P <0.01). CD62p expression showed that the detection of diabetic patients with platelet activation status, prevention of diabetic patients with vascular lesions of great significance.