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1972年10月在美国国立癌研究所(NCI)召开了关于BCG对肺癌治疗的国际讨论会。会议讨论了关于实验性肿瘤系统中对实验动物模型的癌免疫疗法,尤其对黑色素瘤、白血病患者的治疗研究。Rapp氏介绍了对豚鼠-2株用化学致癌造成的肝癌的移植系-10株(同系肿瘤)用BCG得到了肿瘤增殖抑制及消退效果。过去在癌瘤研究中很少使用豚鼠,现在该实验肿瘤系作为癌免疫疗法的一个模型被广泛应用。这次国际讨论会后,在世界各地广泛而迅速地开展起癌免疫疗法的研究,出现一种免疫热。美国最近把这些汇总
In October 1972, an international seminar on the treatment of lung cancer by the BCG was held at the National Cancer Institute (NCI) in the United States. The meeting discussed cancer immunotherapy for experimental animal models in experimental tumor systems, especially for the treatment of melanoma and leukemia patients. Rapp introduced the use of BCG to transplanted line 10 (syngeneic tumors) of guinea pig-2 hepatocarcinoma-induced hepatocarcinomas to obtain tumor growth inhibition and regression effects. In the past, guinea pigs were rarely used in cancer research, and the experimental tumors are now widely used as a model of cancer immunotherapy. After this international seminar, research on cancer immunotherapy was widely and rapidly carried out in various parts of the world, and an immune fever developed. The United States recently summarized these