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目的 :探讨风湿性二尖瓣狭窄患者左心房血液流变学特点及与左心房自回声现象 (SEC)的关系。 方法 :10 2例风湿性二尖瓣狭窄患者 (二尖瓣狭窄组 )于经皮球囊二尖瓣成形术 (PBMV)中自左心房取血液标本进行血液流变学检查。其中 38例患者有左心房 SEC,6 4例患者无左心房 SEC。对照组为 30例同期冠状动脉造影病例。 结果 :1二尖瓣狭窄组各项血液流变学指标均高于对照组 ,有左心房 SEC患者各项血液流变学指标均高于无左心房 SEC患者。2 L ogistic多因素回归分析发现 :二尖瓣狭窄程度、心房颤动、左心房直径、左心房压力均为左心房 SEC的独立预测因子。 结论 :二尖瓣狭窄患者左心房 SEC的形成与血液流变学异常存在密切关系。
Objective: To investigate the hemorheological characteristics of left atrium and the relationship with left atrial spontaneous echo (SEC) in patients with rheumatic mitral stenosis. Methods: Twenty - two patients with rheumatic mitral stenosis (mitral stenosis group) underwent percutaneous balloon mitral valvuloplasty (PBMV) from the left atrium to take blood samples for hemorheological examination. Among them, 38 patients had left atrial septum and 64 patients had no left atrial septum. The control group was 30 cases of coronary angiography at the same period. Results: All the indexes of hemorheology in mitral stenosis group were higher than those in control group. All the indexes of hemorheology in patients with left atrial septum were higher than those without left atrial septum. 2 L ogistic multivariate regression analysis found that: mitral stenosis, atrial fibrillation, left atrial diameter, left atrial pressure were independent predictors of left atrial septum. Conclusions: The formation of SEC in the left atrium in patients with mitral stenosis is closely related to the abnormality of hemorrheology.