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目的:观察正常血压者不同血压水平的危险因素及其与相关疾病的关系。方法:对1 533例血压正常者按血压水平分为3组:血压<120/80 mmHg组,(120～129)/(80～84)mmHg组和(130～139)/(85～89)mmHg组。观察分析年龄、性别、体质量指数(BMI)、腰围、脉压差、血总胆固醇、三酰甘油、空腹血糖以及患冠心病、脑出血和脑梗死的情况与血压水平的关系。结果:年龄、性别、BMI、腰围、脉压差、血总胆固醇、三酰甘油、空腹血糖和冠心病患病率在各血压组之间具有显著性差异(P<0.05,P<0.01);多因素Linear regression分析发现年龄、BMI、腰围和三酰甘油是收缩压的相关因子(P<0.05,P<0.01),而只有腰围是舒张压的相关因子(P<0.01)。结论:正常血压者随着血压水平的升高其心脑血管疾病的危险性也在逐渐增加,在预防血压升高的同时也要预防其危险因素的发生。
Objective: To observe the risk factors of different blood pressure levels in patients with normotensive and its relationship with related diseases. Methods: A total of 1 533 normotensive patients were divided into three groups according to their blood pressure: blood pressure <120/80 mmHg, (120 ~ 129) / (80-84) mmHg and (130 ~ 139) / mmHg group. The relationship between age, gender, body mass index (BMI), waist circumference, pulse pressure difference, total cholesterol, triglyceride, fasting blood glucose, coronary heart disease, cerebral hemorrhage and cerebral infarction were analyzed. Results: The prevalences of age, sex, BMI, waist circumference, pulse pressure, blood total cholesterol, triglyceride, fasting blood glucose and coronary heart disease were significantly different between the various blood pressure groups (P <0.05, P <0.01) Multivariate linear regression analysis showed that age, BMI, waist circumference and triglyceride were the related factors of SBP (P <0.05, P <0.01), while only waist circumference was the related factor of DBP (P <0.01). Conclusions: The risk of cardiovascular and cerebrovascular diseases is gradually increasing with the increase of blood pressure level in patients with normal blood pressure, and preventing the occurrence of risk factors while preventing the increase of blood pressure.