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目的观察原发性肝癌经动脉行化学栓塞术(TACE)与肝动脉留管化疗同步局部高频热疗治疗的临床疗效及其毒副反应。方法 60例患者分为A、B两组,A组30例单纯行TACE治疗、B组30例行TACE后动脉留管化疗联合局部高频热疗,观察比较两组患者的临床效果。结果治疗后B组在肿瘤病灶变化、卡氏评分、疼痛缓解等方面均优于A组,且B组未增加毒副反应。结论行TACE后动脉留管化疗联合局部高频热疗可增加治疗有效率、缓解疼痛、提高患者的生活质量,是治疗原发性肝癌的一种安全、有效的治疗方法。
Objective To observe the clinical efficacy and side effects of simultaneous local high frequency hyperthermia in patients with primary liver cancer undergoing arterial chemoembolization (TACE) and hepatic arterial catheterization. Methods Sixty patients were divided into A and B groups. Thirty patients in group A were treated with TACE only. Thirty patients in group B received TACE and TACE followed by local hyperthermia. The clinical effects of two groups were observed and compared. Results After treatment, B group was better than A group in the changes of tumor focus, Karnofsky score, pain relief and so on, and the B group did not increase the toxicity. Conclusions The TACE combined with local high frequency hyperthermia can increase the therapeutic efficiency, relieve the pain and improve the quality of life of patients. It is a safe and effective treatment for primary liver cancer.