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目的 :对北京 40 2医院 90例药物不良反应报告进行统计分析 ,以了解ADR的发生与性别、年龄和药物之间的关系。方法 :由临床医师、药师、护理人员发现并填写报告 ,经医院ADR监察小组专家分析评价。结果 :90例ADR中合并用药占总数的 5 1.1% ;涉及药物 5 5种 ,其中抗菌药物 2 1种引起ADR 40例占首位 ,12例是中药制剂引起 ,占总数的 13 .3 3 % ;ADR表现以皮肤及附件损害最多 ( 4 9例 ) ,严重的为急性肾功能衰竭导致死亡。结论 :应重视临床合理用药 ,避免和减少不良反应的发生 ,保障患者用药安全。
OBJECTIVE: To analyze 90 ADR reports of 40 2 hospitals in Beijing in order to understand the relationship between ADR occurrence and sex, age and medication. Methods: The clinicians, pharmacists and nurses found and filled in the report and were analyzed and evaluated by the hospital ADR monitoring team. Results: 90 ADRs combined accounted for 51.1% of the total number of ADRs; 55 involved drugs. Of these, 21 were ADRs with antimicrobial agents accounting for the first place, 12 were caused by traditional Chinese medicine, accounting for 13.33% of the total. ADR showed the most damage to the skin and accessories (49 cases), severe acute renal failure caused by death. Conclusion: It is necessary to pay attention to the rational use of drugs, to avoid and reduce the incidence of adverse reactions, to ensure the safety of patients medication.