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1979年11月,我们采集了上海市徐汇区6个月～21岁健康人血液147份,按常规中和试验测定Ⅰ、Ⅱ和Ⅲ型脊髓灰质炎病毒中和抗体,中和抗体阳性率Ⅰ、Ⅱ和Ⅲ型分别为90.48％、90.48％和88.44％。具有三个型抗体的阳性率为80.27％,至少有一个型抗体<1:5者占19.72％,抗体几何平均滴度Ⅰ型为63.04、Ⅱ型为27.75、Ⅲ型为21.83。从年龄分布来看,以6～12个月组抗体水平最低,其次是13～14岁组,8～9岁组抗体水平最高,20～21岁组抗体几何平均滴度在40以下(Ⅰ型35.30,Ⅱ型37.36,Ⅲ型25.15).根据本次调查结果,提出要加强0～2岁组服苗工作,特别要注意6～12个月组.此外,因13～14岁组抗体水平不高,提出除原定自1980年起对7岁儿童加强免疫外,隔6～7年后还要加强免疫。对壮年和老年的免疫状况亦要加以监测。
In November 1979, we collected 147 blood samples of healthy people from 6 months to 21 years old in Xuhui District, Shanghai. The neutralization antibodies of Type I, Type II and Type III were detected by routine neutralization test. The positive rate of neutralizing antibodies , Ⅱ and Ⅲ were 90.48%, 90.48% and 88.44% respectively. The positive rate of the three antibodies was 80.27%, 19.72% with at least one type antibody <1: 5, the geometric mean antibody titers type Ⅰ 63.04, type Ⅱ 27.75 and type Ⅲ 21.83. In terms of age distribution, antibody levels were the lowest in 6 to 12 months, followed by those in 13 to 14 years of age, with the highest antibody levels in 8 to 9 years of age and geometric mean titers of antibodies in 20 to 21 years of age below 40 (type I 35.30, Ⅱ type 37.36, Ⅲ type 25.15) .According to the results of this survey, it is proposed to strengthen the work of group 0 to 2 years of service seedlings, with particular attention to 6 to 12 months group.In addition, due to 13 to 14 years old group antibody levels High, proposed in addition to the original since 1980 to strengthen the immune of 7-year-old children, every 6 to 7 years after the need to strengthen the immune. The immune status of both males and females should also be monitored.