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目的了解围手术期预防性应用抗菌药物指南在心脏外科临床工作中的落实情况。方法选择2007年3-12月医院心脏外科住院手术患者共115例,进行围手术期抗菌药物应用情况调查,同期对临床医师用药指征、用药时间、停药指征进行调查。结果 115例患者发生医院感染4例,医院感染率3.48%;113例患者手术后使用抗菌药物6~10 d。结论医师存在治疗用药倾向,对感染的顾虑是抗菌药物超时使用的重要因素;要规范围手术期预防性使用抗菌药物,需要更进一步做好临床医师的教育工作。
Objective To understand the implementation of perioperative guidelines for the prophylactic use of antimicrobial agents in the clinical work of cardiac surgery. Methods A total of 115 hospitalized patients undergoing cardiothoracic surgery from March 2007 to December 2007 were enrolled. Perioperative antibacterials application was investigated. At the same time, clinical indications, medication duration and withdrawal indications were investigated. Results Among the 115 cases, 4 cases were nosocomial infection and 3.48% were hospital infection. One hundred and thirteen patients were treated with antibiotics for 6-10 days after operation. Conclusion The physician has the tendency to treat medication and the infection is an important factor in overtime use of antimicrobial drugs. To standardize the prophylactic use of antimicrobial agents in perioperative period, clinicians need to be further educated.