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目的了解清远市区小学生HBV感染情况,为乙型肝炎的防治工作提供依据。方法 2008年10—11月采用整群抽样的方法,抽取清远市区小学一年级至六年级在校学生的血样,用酶联免疫吸附试验(ELISA)法进行乙型肝炎表面抗原(HBsAg)、乙型肝炎表面抗体(HBsAb)检测,对检测结果进行统计分析。结果共调查16142名在校小学生,HBsAg总携带率为1.32%,且随年龄的增长呈上升趋势(P<0.01);HBsAb阳性率为49.57%,阳性率随年龄增长呈下降趋势(P<0.01);男女生HBsAg阳性率比较,差异无统计学意义,男生HBsAb阳性率45.70%,低于女生50.39%(P<0.01)。结论清远市区小学生HBsAg携带率低于全国平均水平,HBsAb阳性率高于全国平均水平,应继续推广乙肝疫苗的加强免疫,加强乙型肝炎病毒表面抗体的检测,加大乙型肝炎的综合防治力度。
Objective To understand the prevalence of HBV infection among primary school students in Qingyuan City and provide evidence for the prevention and treatment of hepatitis B. Methods From October to November, 2008, a cluster sampling method was used to collect blood samples of freshmen from Grade 1 to Grade 6 in primary school of Qingyuan City. HBsAg, HBsAg and HBsAg were detected by enzyme linked immunosorbent assay (ELISA) Hepatitis B surface antibody (HBsAb) test, the test results were statistically analyzed. Results A total of 16142 schoolchildren were enrolled in this study. The total HBsAg carrier rate was 1.32% and increased with age (P <0.01). The positive rate of HBsAb was 49.57%, and the positive rate decreased with age (P <0.01) ). There was no significant difference in the positive rate of HBsAg between boys and girls. The positive rate of HBsAb was 45.70% in boys and 50.39% in girls (P <0.01). Conclusion The carrying rate of HBsAg among primary school students in Qingyuan is lower than the national average level, and the positive rate of HBsAb is higher than the national average. Therefore, we should continue to promote the booster immunization of hepatitis B vaccine, strengthen the detection of hepatitis B virus surface antibody and intensify the comprehensive prevention and treatment of hepatitis B Strength.