肺泡蛋白沉积症(pulmonary alveolar proteinosis,PAP)于1958年由Rosen等[1]首先报道,是一种少见的肺部弥漫性疾病,各个年龄均可发病,以成人多见。临床特点为咳嗽、气促、进行性呼吸困难。PAP可分为自身免疫性、先天性和继发性,本文主要介绍我院近期诊断的1例继发于慢性粒细胞性白血病的PAP。临床资料患者男性,59岁。因“咳嗽气喘4个月余”于2013年6月入院。患者2012年5月于某医院体检发现白细胞显著增高(当时胸部X线片正常),后经血液及骨髓等检查确诊为慢性粒细胞性白血病(慢性期),自服中药治疗,具体药物及 Pulmonary alveolar proteinosis (PAP), first reported by Rosen et al [1] in 1958, is a rare pulmonary diffuse disease with onset in all age and more common in adults. Clinical features of cough, shortness of breath, progressive dyspnea. PAP can be divided into autoimmune, congenital and secondary, this article describes the recent diagnosis of a hospital in our hospital secondary to chronic myeloid leukemia in the PAP. Clinical data Male patient, 59 years old. Because “cough and asthma more than 4 months ” was admitted in June 2013. Patients in May 2012 in a hospital physical examination found that leukocytes was significantly higher (at that time chest X-ray was normal), after blood and bone marrow examination confirmed the diagnosis of chronic myeloid leukemia (chronic phase), self-serving Chinese medicine, specific drugs and