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肿瘤的生长和转移与其新生血管的生成密切相关,体内外实验表明,TNP-470可抑制血管内皮细胞的增殖,影响肿瘤血管生成,控制肿瘤的生长和转移。本文对TNP-470与其它疗法联合应用抗肿瘤治疗的研究现状作一综述。
The growth and metastasis of tumors are closely related to the generation of new blood vessels. In vivo and in vitro experiments show that TNP-470 can inhibit the proliferation of vascular endothelial cells, affect tumor angiogenesis, and control the growth and metastasis of tumors. This article reviews the research status of the combination of TNP-470 and other therapies for anti-tumor therapy.