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目的观察平阳霉素和地塞米松联用治疗小儿颌面部血管瘤的临床疗效。方法对45例颌面部血管瘤患儿采用平阳霉素、地塞米松及利多卡因进行瘤体多点腔内注射治疗,注射后至瘤体表面皮肤或黏膜变白,用无菌棉球按压针孔2-3min,治疗后随访1年,观察患儿临床疗效、全身和局部不良反应。结果 45例患儿中,治愈34例(75.56%),基本治愈8例(17.77%),有效3例(6.67%),总有效率为100%,随访1年后患儿均未见血管瘤复发。结论平阳霉素联合地塞米松治疗小儿颌面部血管瘤临床疗效显著,且操作简单、微创,全身和局部不良反应少,值得临床推广应用。
Objective To observe the clinical efficacy of pingyangmycin and dexamethasone in the treatment of maxillofacial hemangiomas in children. Methods Forty-five patients with maxillofacial hemangiomas were treated with bleomycin, dexamethasone and lidocaine for multiple intracavitary injection. After injection, the skin or mucosa of the tumor surface was whitened. Sterile cotton balls Press the pinhole 2-3min, followed up for 1 year after treatment to observe the clinical efficacy of children, systemic and local adverse reactions. Results Of 45 children, 34 (75.56%) were cured, 8 were cured (17.77%), 3 were effective (6.67%) and the total effective rate was 100% relapse. Conclusion Pingyangmycin combined with dexamethasone treatment of children with maxillofacial hemangioma clinical significant effect, and simple operation, minimally invasive, systemic and local adverse reactions, it is worth promoting the clinical application.