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作者应用大肠杆菌研究梗阻性黄疸兔的网状内皮系统（ＲＥＳ）功能状况，提示胆总管结扎（ＣＢＤＬ）１周后兔清除大肠杆菌的能力低于模拟手术组（Ｐ＜０．０５），校正吞噬指数也降低（Ｐ＜０．０１）。ＣＢＤＬ３周后，实验兔清除大肠杆菌的能力和校正吞噬指数未见进一步下降，说明梗阻性黄疸时间延长并不进行性加重ＲＥＳ功能的抑制。肝枯否细胞和肺泡巨噬细胞的分布和超微结构各组间无明显差异，表明梗阻性黄疸对巨噬细胞的结构无明显影响，ＲＥＳ功能抑制可能是细胞吞噬和溶解细菌的速度减慢所致。
The authors used Escherichia coli to study the function of reticuloendothelial system (RES) in obstructive jaundice rabbits. The results showed that the ability of E. coli to clear E.coli in rabbits one week after choledocholithiasis (CBDL) was lower than that in the simulated surgery group (P <0.05) Phagocytic index also decreased (P <0.01). CBDL3 weeks later, the ability of experimental rabbits to clear Escherichia coli and correction of phagocytic index no further decline, indicating that prolonged obstructive jaundice does not exacerbate the inhibition of RES function. The distribution and ultrastructure of hepatic Kupffer cells and alveolar macrophages were not significantly different between groups, indicating that obstructive jaundice had no significant effect on the structure of macrophages, and the inhibition of RES function might be due to the slowing of the rate of phagocytosis and lytic bacteria Due.