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已有报道,成人精神病患者使用抗精神病药物治疗时,可能发生静脉血栓栓塞(VTE)。本文旨在评估非典型的和传统的抗精神药物对老年患者产生VTE入院的风险影响。作者对5个州疗养院的疗养员进行了回顾性队列研究,使用一组数据库中的数据,选取19940名新的精神病药物服用者和112078名未服药者。静脉血栓栓塞的住院病人出院时的主要诊断是在6个月的随访期间使用结算住院病人医疗保险金确定的。用COX比例风险模式来评估对混淆因子校正的影响。结果:每年VTE入院率为0.91/100人年,静脉血栓栓塞占事件的77.6%,肺栓塞占22.4%。相对于未用者,
It has been reported that venous thromboembolism (VTE) may occur in adults with psychotic disorders when treated with antipsychotics. This article aims to assess the impact of atypical and traditional antipsychotics on the risk of developing VTE admission in elderly patients. The authors conducted a retrospective cohort study of convalescent staff in five state sanitariums using a set of data from a database of 19940 new psychotropic drug users and 112,078 non-responders. The main diagnosis of hospital discharge of venous thromboembolism at discharge was confirmed by the settlement of inpatient medical insurance money during the 6-month follow-up period. Use the COX Proportional Risk Model to evaluate the effect on confusion factor correction. Results: The annual VTE admission rate was 0.91 / 100 person-years, with venous thromboembolism accounting for 77.6% and pulmonary embolism accounting for 22.4%. Relative to the unused,