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为了解除中等到严重的急性疼痛和降低慢性恶性疼痛的程度,麻醉性镇痛药最常用肌注给药。与口服给药相比,注射途径具有开始作用更迅速和避免生物利用度变异的优点。作者测定并比较了吗啡和美散痛三角肌注射和臀肌注射的血浆浓度和镇痛效应。给32例术后癌症患者于三角肌和臀肌注射吗啡。44例患者注射美散痛。术前
Narcotic analgesics are most commonly administered intramuscularly to relieve moderate to severe acute pain and to reduce the extent of chronic malignant pain. In contrast to oral administration, the route of injection has the advantage of starting more rapidly and avoiding variations in bioavailability. The authors measured and compared the plasma concentrations and analgesic effects of delphinidazole and morphine for pain relief in morphine and sore throat. To 32 patients with postoperative cancer in the deltoid and gluteal injection of morphine. Forty-four patients received U.S.A. Preoperative