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目的探讨早期乳腺癌保乳治疗的中、远期临床疗效。方法观察52例Ⅰ、Ⅱ期原发性乳腺癌患者,51例施行保乳切除并腋窝淋巴结清扫,术后辅以化疗、放疗、内分泌等综合治疗,另外1例因二次切缘阳性而行改良根治术。结果保乳手术局部复发率和远处转移率分别为5.9%、3.9%,3、5年生存率分别为96.08%、92.16%。患者对残乳自我评价的满意程度为82.4%(42/51),其中良好者占58.8%(30/51)。结论保乳手术联合术后辅助放疗和全身化疗治疗早期乳腺癌安全可行。
Objective To investigate the mid-term and long-term clinical efficacy of breast-conserving therapy for early breast cancer. Methods Fifty-two patients with stage Ⅰ and Ⅱ primary breast cancer were observed. Fifty-one patients underwent conservative breast-conserving resection and axillary lymph node dissection. The patients were treated with chemotherapy, radiotherapy and endocrine therapy. One case was positive for secondary cut-off Modified radical mastectomy. Results The local recurrence rate and distant metastasis rate of breast-conserving surgery were 5.9%, 3.9%, 3.5 years respectively, 96.08%, 92.16%. The satisfaction rate of patients with self-evaluation of residual milk was 82.4% (42/51), of which 58.8% (30/51) were good. Conclusion The combination of breast-conserving surgery and postoperative adjuvant radiotherapy and systemic chemotherapy for the treatment of early breast cancer is safe and feasible.