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老年慢性支气管炎(简称老慢支)是老年人的难治性常见病和多发病,临床统计约占老年人总数的10—15%。大多数40岁以后发病,且男性多于女性,初期症状轻浅不易引起重视,待病变持续进展并发展成为阻塞性肺气肿以至肺源性心脏病时治疗效果往往欠佳。由于长期的小气道感染,不规范地使用多种抗生素,细菌耐药性增强,加之50岁以上的老人肾功能及机体代谢明显下降,稍一疏忽便会出现毒性反应,所以,临床上在抗生素的选用及联用时要充分引起重视。我们自1990年12月至1997年2月对100例老年慢性支气管炎仅就使用抗生素治疗的体会报告如下:
Elderly chronic bronchitis (referred to as the old chronic bronchitis) is a common and frequently-occurring disease refractory to the elderly, clinical statistics account for about 10-15% of the total number of the elderly. Most of the incidence after the age of 40, and more men than women, the initial symptoms of light is not easy to pay attention, until the disease continues to progress and develop into obstructive emphysema and pulmonary heart disease often poor treatment. Due to long-term small airway infections, non-standard use of a variety of antibiotics, bacterial resistance increased, combined with the elderly over the age of 50 renal function and body metabolism decreased significantly, there will be a little careless toxicity, so clinically in the antibiotics The selection and use of the full attention should be given. We report from December 1990 to February 1997 on the experience of 100 elderly patients with chronic bronchitis treated with antibiotics only: