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目的探讨早期干预对妊娠期糖尿病妊娠结局的影响。方法分析确诊为妊娠期糖尿病的98例患者的临床资料。根据血糖情况分为控制良好组58例(A组)和不佳组40例(B组),按妊娠期糖尿病诊断时间,以孕28周为界,又分为早期诊断组50例(早诊组)和晚期诊断组48例(晚诊组)。比较妊娠结局与早期诊断及干预的关系。结果 B组妊娠期高血压疾病、胎膜早破、羊水过多、新生儿窒息、早产发生率明显高于A组;晚诊组妊娠期高血压疾病、胎膜早破、羊水过多、巨大儿及早产发生率明显高于早诊组,相比差异均有统计学意义(P<0.05),而剖宫产率、胎儿窘迫、新生儿窒息的发生率相比差异无统计学意义(P>0.05)。结论早期发现及有效控制血糖在正常范围内可明显降低妊娠期糖尿病孕妇母婴并发症的发生率。故对早期诊断和治疗妊娠期糖尿病有重要的临床意义。
Objective To investigate the effect of early intervention on pregnancy outcome of gestational diabetes mellitus. Methods Clinical data of 98 patients diagnosed with gestational diabetes mellitus were analyzed. According to the blood glucose, 58 cases (control group A) and 40 cases (control group B) were divided into two groups: control group (group B) and gestational diabetes mellitus Group) and 48 cases of late diagnosis group (late diagnosis group). The relationship between pregnancy outcome and early diagnosis and intervention was compared. Results The incidence of gestational hypertension, premature rupture of membranes, polyhydramnios, neonatal asphyxia and preterm birth in group B were significantly higher than those in group A. The incidence of gestational hypertension, premature rupture of membranes, polyhydramnios, The incidence of preterm birth and premature birth was significantly higher than that of the early diagnosis group (P <0.05), while there was no significant difference in the incidence of cesarean section, fetal distress and neonatal asphyxia (P > 0.05). Conclusion Early detection and effective control of blood glucose in the normal range can significantly reduce the incidence of maternal and neonatal complications of pregnant women with gestational diabetes. Therefore, the early diagnosis and treatment of gestational diabetes has important clinical significance.