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对310例HBsAg携带者的e系统经2.5～6年(平均4.2年)的追踪观察结果表明,85例e 抗原阳性者中66人阴转(占77.6%),平均每年自然阴转率为18.5%,其中从e 抗原向e 抗体的血清转换占20%。44例e 抗体阳性者中有52.3%的人阴转,有1例(占2.3%)向e 抗原逆转,同时肝炎急性发作。181例e 系统阴性者有86.2%仍阴性,11.6%出现抗体。e 抗原阴阳交迭现象,在e 抗原阳性者中占18.8%(16/85),在e 系统阴性者中占7.7%(14/181),两者有非常显著性差别。影响e 抗原阴转的因素有时间,性别与HBsAg 滴度。
The follow-up results of e system of 310 HBsAg carriers from 2.5 to 6 years (mean 4.2 years) showed that 66 of 85 e antigen-positive patients were negative (77.6%) with an average annual natural negative conversion rate of 18.5 %, Where seroconversion from e antigen to e antibody accounted for 20%. In 44 of the 44 e-antibody positive individuals, 52.3% of the patients were negative, and 1 (2.3%) reversed the e antigen, with an acute attack of hepatitis. Of the 181 e-negative cases, 86.2% were still negative and 11.6% showed antibodies. e antigen overlap, accounting for 18.8% (16/85) of those with e antigen positive and 7.7% (14/181) of those with e-negative, both of which have very significant differences. The factors that affect the e antigen negative turn with time, sex and HBsAg titers.