心脏发育是一个涉及到多种基因在不同时间和不同空间的先后表达与相互作用的复杂过程,其中任何一个基因发生质或量的表达异常都可能会影响心脏发育,导致先天性心脏病的发生。对先天性心脏病基因方面的研究有助于为该病提供更多临床检测,为遗传咨询提供理论依据,对其产前诊断和宫内干预的开展具有重大的指导意义。 Cardiac development is a complex process involving the expression and interaction of multiple genes at different times and spaces. Any abnormal or abnormal gene expression may affect the development of the heart and lead to the occurrence of congenital heart disease . The research on gene of congenital heart disease will help to provide more clinical tests for the disease and provide a theoretical basis for genetic counseling, which is of great guiding significance to the prenatal diagnosis and intrauterine intervention.