甲皱毛细血管的改变是进行性系统性硬化症中脏器受累的标记

来源 :国外医学.皮肤病学分册 | 被引量 : 0次 | 上传用户:sunshineaigeng
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风湿病病谱包括具有血管系统异常的各种疾病。硬皮病、皮肌炎、红斑狼疮等多种结缔组织病都有明确的甲皱毛细血管的改变。本文试图重新检验进行性系统性硬化症(PSS)对毛细血管异常与免疫学异常及脏器受累间的关系。40例病人均符合 ARA 的诊断标准。平均年龄44岁(29~72岁);病程6个月至14年;男8例,女32例。用放大60倍的 Wild M_3毛细血管镜检查所有手指和甲皱。毛细血管变化按 Maricq 标准分级,毛细血管减少的分级按 Minkin 和 Rabham 标准进行。所有病人均进行了完整的体格检查和实验室检查,包括:ANA 滴度、DNA 结合率、冷球蛋白、循环免疫复合物、24小时尿肌酐清除率。其他检查包括食管、胃、肺的 X 光摄片,肺功能、心脏超声检 The spectrum of rheumatism includes various diseases that have an abnormal vascular system. Scleroderma, dermatomyositis, lupus and other connective tissue diseases have a clear change of a capillary capillaries. This article attempts to re-examine the relationship between progressive systemic sclerosis (PSS) and capillary abnormalities and immunological abnormalities and organ involvement. All 40 patients met the diagnostic criteria of ARA. The average age of 44 years (29 to 72 years); duration of 6 months to 14 years; 8 males and 32 females. Examine your fingers and nail fold with a Wild M_3 capillary tube at a magnification of 60x. Capillary changes were graded according to the Maricq criteria and grading of capillaries was performed according to the Minkin and Rabham standards. All patients underwent complete physical and laboratory tests including ANA titers, DNA binding rates, cryoglobulins, circulating immune complexes, and urinary creatinine clearance at 24 hours. Other tests include esophageal, stomach, lung X-ray, pulmonary function, cardiac ultrasonography
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